Ultrasound-Sensitive Liposomes for Triggered Macromolecular Drug Delivery: Formulation and In Vitro Characterization

Mistletoe lectin-1 (ML1) is a nature-derived macromolecular cytotoxin that potently induces apoptosis in target cells. Non-specific cytotoxicity to normal cells is one of the major risks in its clinical application, and we therefore propose to encapsulate ML1 in a nanocarrier that can specifically r...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: de Matos, Maria B. C., Deckers, Roel, van Elburg, Benjamin, Lajoinie, Guillaume, de Miranda, Bárbara S., Versluis, Michel, Schiffelers, Raymond, Kok, Robbert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906197/
https://ncbi.nlm.nih.gov/pubmed/31866867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01463
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