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Prolonged ovarian storage of mature Drosophila oocytes dramatically increases meiotic spindle instability

Human oocytes frequently generate aneuploid embryos that subsequently miscarry. In contrast, Drosophila oocytes from outbred laboratory stocks develop fully regardless of maternal age. Since mature Drosophila oocytes are not extensively stored in the ovary under laboratory conditions like they are i...

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Foilsithe in:eLife
Main Authors: Greenblatt, Ethan J, Obniski, Rebecca, Mical, Claire, Spradling, Allan C
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2019
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905857/
https://ncbi.nlm.nih.gov/pubmed/31755866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49455
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