An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of Epilepsy

The sparse activity of hippocampal dentate gyrus (DG) granule cells (GCs) is thought to be critical for cognition and behavior, whereas excessive DG activity may contribute to disorders such as temporal lobe epilepsy (TLE). Glutamatergic mossy cells (MCs) of the DG are potentially critical to normal...

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Udgivet i:Cell Rep
Main Authors: Botterill, Justin J., Lu, Yi-Ling, LaFrancois, John J., Bernstein, Hannah L., Alcantara-Gonzalez, David, Jain, Swati, Leary, Paige, Scharfman, Helen E.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905501/
https://ncbi.nlm.nih.gov/pubmed/31775052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.100
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