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Perforin gene PRF1 c.900C> T polymorphism and HIV-1 vertical transmission

Perforin-1, a component of the immune system, is able to control Human Immunodeficiency Virus-1 (HIV-1) replication and could be involved in HIV-1 mother-to-child transmission (MTCT). This study aims at evaluating the role of the c.900C > T PRF1 gene (encoding for perforin-1) polymorphism (rs8858...

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Publicado en:Genet Mol Biol
Autores principales: Zupin, Luisa, Polesello, Vania, Kamada, Anselmo Jiro, Gratton, Rossella, Segat, Ludovica, Kuhn, Louise, Crovella, Sergio
Formato: Artigo
Lenguaje:Inglês
Publicado: Sociedade Brasileira de Genética 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905447/
https://ncbi.nlm.nih.gov/pubmed/31188937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1678-4685-GMB-2018-0243
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