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1,25-(OH)(2)D(3)/Vitamin D receptor alleviates systemic lupus erythematosus by downregulating Skp2 and upregulating p27

BACKGROUND: Recent evidence has suggested that the 1,25(OH)(2)D(3)/Vitamin D receptor (VDR) acts to suppress the immune response associated with systemic lupus erythematosus (SLE), a serious multisystem autoimmune disease. Hence, the aim of the current study was to investigate the mechanism by which...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Liu, Dan, Fang, Yu-Xuan, Wu, Xia, Tan, Wei, Zhou, Wei, Zhang, Yu, Liu, Yan-Qing, Li, Guo-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905035/
https://ncbi.nlm.nih.gov/pubmed/31823770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0488-2
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