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Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Inflammation alters bone marrow hematopoiesis to favor the production of innate immune effector cells at the expense of lymphoid cells and erythrocytes. Furthermore, proinflammatory cytokines inhibit steady-state erythropoiesis, which leads to the development of anemia in diseases with chronic infla...

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Detalles Bibliográficos
Publicado en:Sci Signal
Autores principales: Bennett, Laura F., Liao, Chang, Quickel, Michael D., Yeoh, Beng San, Vijay-Kumar, Matam, Hankey-Giblin, Pamela, Prabhu, K. Sandeep, Paulson, Robert F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904953/
https://ncbi.nlm.nih.gov/pubmed/31506384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aap7336
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