Novel and safe single-dose treatment of cutaneous leishmaniasis with implantable amphotericin B-loaded microparticles

The development of an effective amphotericin B (AmB) topical formulation to replace the systemically toxic injections currently used in cutaneous leishmaniasis (CL) treatment is challenging due to poor absorption through the skin. Aiming at an effective local chemotherapy, we designed PLGA (poly(lac...

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Vydáno v:Int J Parasitol Drugs Drug Resist
Hlavní autoři: Sousa-Batista, Ariane J., Pacienza-Lima, Wallace, Ré, Maria Inês, Rossi-Bergmann, Bartira
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
Témata:
Includes articles from the special issue “Novel therapies for cutaneous leishmaniasis”, pp. 106 - 179
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904829/
https://ncbi.nlm.nih.gov/pubmed/31331828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2019.06.001
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