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Novel and safe single-dose treatment of cutaneous leishmaniasis with implantable amphotericin B-loaded microparticles

The development of an effective amphotericin B (AmB) topical formulation to replace the systemically toxic injections currently used in cutaneous leishmaniasis (CL) treatment is challenging due to poor absorption through the skin. Aiming at an effective local chemotherapy, we designed PLGA (poly(lac...

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Bibliografske podrobnosti
izdano v:Int J Parasitol Drugs Drug Resist
Main Authors: Sousa-Batista, Ariane J., Pacienza-Lima, Wallace, Ré, Maria Inês, Rossi-Bergmann, Bartira
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904829/
https://ncbi.nlm.nih.gov/pubmed/31331828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2019.06.001
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