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Systemic Delivery of CRISPR/Cas9 Targeting HPV Oncogenes Is Effective at Eliminating Established Tumors

The recent advancements in CRISPR/Cas9 engineering have resulted in the development of more targeted and potentially safer gene therapies. The challenge in the cancer setting is knowing the driver oncogenes responsible, and the translation of these therapies is hindered by effective and safe deliver...

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Publicat a:Mol Ther
Autors principals: Jubair, Luqman, Fallaha, Sora, McMillan, Nigel A.J.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904748/
https://ncbi.nlm.nih.gov/pubmed/31537455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.08.012
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