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Customisation and validation of a low-volume plasma renin activity immunoassay: Enabling of regulatory compliant determination in paediatric trials

OBJECTIVES: Investigations of plasma renin activity (PRA) in children are urgently required. Small-volume, regulatory guideline compliant, bioanalytical assays tailored for paediatric application could facilitate to overcome this hurdle. Ethical constraints given e.g. by the European Medicines Agenc...

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Detalhes bibliográficos
Publicado no:Pract Lab Med
Main Authors: Suessenbach, F.K., Tins, J., Burckhardt, B.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904673/
https://ncbi.nlm.nih.gov/pubmed/31867426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plabm.2019.e00144
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