CD31 acts as a checkpoint molecule and is modulated by FcγR-mediated signaling in monocytes

Monocytes and macrophages express Fc gamma Receptors (FcγR) that engage IgG immune complexes such as antibody-opsonized pathogens or cancer cells to destroy them by various mechanisms including phagocytosis. FcγR-mediated phagocytosis is regulated by the concerted actions of activating FcγR and inhi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Merchand-Reyes, Giovanna, Robledo-Avila, Frank H., Buteyn, Nathaniel J., Gautam, Shalini, Santhanam, Ramasamy, Fatehchand, Kavin, Mo, Xiaokui, Partida-Sanchez, Santiago, Butchar, Jonathan P., Tridandapani, Susheela
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904527/
https://ncbi.nlm.nih.gov/pubmed/31732534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900059
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