Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) caused by PKD1 mutations is one of the most common hereditary disorders. However, the key pathological processes underlying cyst development and exacerbation in pre-symptomatic stages remain unknown, because rodent models do not recapitulate criti...

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Publicado no:Nat Commun
Main Authors: Tsukiyama, Tomoyuki, Kobayashi, Kenichi, Nakaya, Masataka, Iwatani, Chizuru, Seita, Yasunari, Tsuchiya, Hideaki, Matsushita, Jun, Kitajima, Kahoru, Kawamoto, Ikuo, Nakagawa, Takahiro, Fukuda, Koji, Iwakiri, Teppei, Izumi, Hiroyuki, Itagaki, Iori, Kume, Shinji, Maegawa, Hiroshi, Nishinakamura, Ryuichi, Nishio, Saori, Nakamura, Shinichiro, Kawauchi, Akihiro, Ema, Masatsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904451/
https://ncbi.nlm.nih.gov/pubmed/31822676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13398-6
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