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Virtual clinical trials identify effective combination therapies in ovarian cancer

A major issue in oncology is the high failure rate of translating preclinical results in successful clinical trials. Using a virtual clinical trial simulations approach, we present a mathematical framework to estimate the added value of combinatorial treatments in ovarian cancer. This approach was a...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Kozłowska, Emilia, Vallius, Tuulia, Hynninen, Johanna, Hietanen, Sakari, Färkkilä, Anniina, Hautaniemi, Sampsa
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904444/
https://ncbi.nlm.nih.gov/pubmed/31822719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55068-z
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