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Impact of Polypharmacy and P-Glycoprotein- and CYP3A4-Modulating Drugs on Safety and Efficacy of Oral Anticoagulation Therapy in Patients with Atrial Fibrillation

PURPOSE: To study whether polypharmacy or drug–drug interactions have differential effect on safety and efficacy in patients treated with direct oral anticoagulants (DOACs) versus warfarin. METHODS: We performed a systematic review and meta-analysis of studies that randomized patients with atrial fi...

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Detalhes bibliográficos
Publicado no:Cardiovasc Drugs Ther
Main Authors: Harskamp, Ralf E., Teichert, Martina, Lucassen, Wim A. M., van Weert, Henk C. P. M., Lopes, Renato D.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904377/
https://ncbi.nlm.nih.gov/pubmed/31520256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-019-06907-8
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