Hemorheological Alterations and Oxidative Damage in Sickle Cell Anemia

Sickle cell anemia (SCA) is the most common hereditary disorder of hemoglobin (Hb) characterized by a mutation in the β globin gene, which leads to synthesis of HbS a hemoglobin which, under hypoxic conditions, gels and leading to the sickling of the red blood cells (RBC). The dehydration of the RBC...

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Bibliographische Detailangaben
Veröffentlicht in:Front Mol Biosci
Hauptverfasser: Caprari, Patrizia, Massimi, Sara, Diana, Loretta, Sorrentino, Francesco, Maffei, Laura, Materazzi, Stefano, Risoluti, Roberta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Molecular Biosciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904369/
https://ncbi.nlm.nih.gov/pubmed/31867341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00142
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