Bidirectional Synaptic Plasticity Is Driven by Sex Neurosteroids Targeting Estrogen and Androgen Receptors in Hippocampal CA1 Pyramidal Neurons

Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus. While estrogens facilitate long-term potentiation (LTP), androgens are involved in the induction of long-term depression (LTD) and...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Tozzi, Alessandro, Durante, Valentina, Manca, Paolo, Di Mauro, Michela, Blasi, Juan, Grassi, Silvarosa, Calabresi, Paolo, Kawato, Suguru, Pettorossi, Vito Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904272/
https://ncbi.nlm.nih.gov/pubmed/31866827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00534
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