Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion

Malignant astrocytomas are highly invasive into adjacent and distant regions of the normal brain. Understanding and targeting cancer cell invasion is an important therapeutic approach. Cell invasion is a complex process that replies on many signaling pathways including the mitogen-activated protein...

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Bibliographic Details
Published in:Int J Oncol
Main Authors: Al-Dimassi, Saleh, Salloum, Gilbert, Saykali, Bechara, Khoury, Oula, Liu, Shihui, Leppla, Stephen H., Abi-Habib, Ralph, El-Sibai, Mirvat
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904103/
https://ncbi.nlm.nih.gov/pubmed/26984023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3431
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