Reduced Glutamate in the Medial Prefrontal Cortex Is Associated With Emotional and Cognitive Dysregulation in People With Chronic Pain

A decrease in glutamate in the medial prefrontal cortex (mPFC) has been extensively found in animal models of chronic pain. Given that the mPFC is implicated in emotional appraisal, cognition and extinction of fear, could a potential decrease in glutamate be associated with increased pessimistic thi...

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Vydáno v:Front Neurol
Hlavní autoři: Naylor, Brooke, Hesam-Shariati, Negin, McAuley, James H., Boag, Simon, Newton-John, Toby, Rae, Caroline D., Gustin, Sylvia M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neurology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903775/
https://ncbi.nlm.nih.gov/pubmed/31849800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.01110
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