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Reduced Glutamate in the Medial Prefrontal Cortex Is Associated With Emotional and Cognitive Dysregulation in People With Chronic Pain

A decrease in glutamate in the medial prefrontal cortex (mPFC) has been extensively found in animal models of chronic pain. Given that the mPFC is implicated in emotional appraisal, cognition and extinction of fear, could a potential decrease in glutamate be associated with increased pessimistic thi...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Naylor, Brooke, Hesam-Shariati, Negin, McAuley, James H., Boag, Simon, Newton-John, Toby, Rae, Caroline D., Gustin, Sylvia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903775/
https://ncbi.nlm.nih.gov/pubmed/31849800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.01110
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