Effects of metformin administration on endocrine-metabolic parameters, visceral adiposity and cardiovascular risk factors in children with obesity and risk markers for metabolic syndrome: A pilot study

BACKGROUND: Metformin treatment (1000–2000 mg/day) over 6 months in pubertal children and/or adolescents with obesity and hyperinsulinism is associated with a reduction in body mass index (BMI) and the insulin resistance index (HOMA-IR). We aimed to ascertain if long-term treatment (24 months) with...

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Publicat a:PLoS One
Autors principals: Bassols, Judit, Martínez-Calcerrada, José-María, Osiniri, Inés, Díaz-Roldán, Ferran, Xargay-Torrent, Silvia, Mas-Parés, Berta, Dorado-Ceballos, Estefanía, Prats-Puig, Anna, Carreras-Badosa, Gemma, de Zegher, Francis, Ibáñez, Lourdes, López-Bermejo, Abel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903728/
https://ncbi.nlm.nih.gov/pubmed/31821361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0226303
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