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Disruption of transcription-translation coordination in Escherichia coli leads to premature transcriptional termination

Tight coordination between transcription and translation is crucial to maintaining the integrity of gene expression in bacteria. How bacteria manage to coordinate these two processes remains unclear. Possible direct physical coupling between the RNA polymerase and ribosome has been intensely investi...

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Veröffentlicht in:Nat Microbiol
Hauptverfasser: Zhu, Manlu, Mori, Matteo, Hwa, Terence, Dai, Xiongfeng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903697/
https://ncbi.nlm.nih.gov/pubmed/31451774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0543-1
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