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Disruption of transcription-translation coordination in Escherichia coli leads to premature transcriptional termination

Tight coordination between transcription and translation is crucial to maintaining the integrity of gene expression in bacteria. How bacteria manage to coordinate these two processes remains unclear. Possible direct physical coupling between the RNA polymerase and ribosome has been intensely investi...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Zhu, Manlu, Mori, Matteo, Hwa, Terence, Dai, Xiongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6903697/
https://ncbi.nlm.nih.gov/pubmed/31451774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0543-1
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