The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model

Pattern recognition receptors (PRRs) are key elements in the innate immune response. Formyl peptide receptor (FPR) 2 is a PRR that, in addition to proinflammatory, pathogen-derived compounds, also recognizes the anti-inflammatory endogenous ligand annexin A1 (AnxA1). Because the contribution of this...

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Vydáno v:FASEB J
Hlavní autoři: Schloer, Sebastian, Hübel, Nicole, Masemann, Dörthe, Pajonczyk, Denise, Brunotte, Linda, Ehrhardt, Christina, Brandenburg, Lars-Ove, Ludwig, Stephan, Gerke, Volker, Rescher, Ursula
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2019
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902725/
https://ncbi.nlm.nih.gov/pubmed/31398292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901265R
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