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CPT1a gene expression reverses the inflammatory and anti-phagocytic effect of 7-ketocholesterol in RAW264.7 macrophages

BACKGROUND: Macrophage are specialized cells that contributes to the removal of detrimental contents via phagocytosis. Lipid accumulation in macrophages, whether from phagocytosis of dying cells or from circulating oxidized low-density lipoproteins, alters macrophage biology and functionality. It is...

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Bibliografiske detaljer
Udgivet i:Lipids Health Dis
Main Authors: Calle, Priscila, Muñoz, Angeles, Sola, Anna, Hotter, Georgina
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902499/
https://ncbi.nlm.nih.gov/pubmed/31823799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-019-1156-7
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