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Therapeutic effect of nanoliposomal PCSK9 vaccine in a mouse model of atherosclerosis
BACKGROUND: Proprotein convertase subtilisin/kexin 9 (PCSK9) is an important regulator of low-density lipoprotein receptor (LDLR) and plasma levels of LDL cholesterol (LDL-C). PCSK9 inhibition is an efficient therapeutic approach for the treatment of dyslipidemia. We tested the therapeutic effect of...
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| Publicado en: | BMC Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6902459/ https://ncbi.nlm.nih.gov/pubmed/31818299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-019-1457-8 |
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