Germline Polymorphisms in the Nuclear Receptors PXR and VDR as Novel Prognostic Markers in Metastatic Colorectal Cancer Patients Treated With FOLFIRI

Nuclear receptors act as mediators of cancer-related inflammation and gene expression. They have a regulatory effect on genes encoding proteins related to drug adsorption, distribution, metabolism, and excretion. The aim of the present study was to highlight novel prognostic markers among polymorphi...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: De Mattia, Elena, Polesel, Jerry, Roncato, Rossana, Labriet, Adrien, Bignucolo, Alessia, Dreussi, Eva, Romanato, Loredana, Guardascione, Michela, Buonadonna, Angela, D'Andrea, Mario, Lévesque, Eric, Jonker, Derek, Couture, Félix, Guillemette, Chantal, Cecchin, Erika, Toffoli, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901926/
https://ncbi.nlm.nih.gov/pubmed/31850208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01312
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