Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway

Acute myeloid leukemia (AML) is a common type of hematological malignancy that can progress rapidly. AML has a poor prognosis and a high incidence of relapse due to therapeutic resistance. Azelaic acid (AZA), a small molecular compound is known to exhibit antitumor effect on various tumor cells. Thi...

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Vydáno v:Front Pharmacol
Hlavní autoři: Dongdong, Zhang, Jin, Yanxia, Yang, Tian, Yang, Qian, Wu, Balu, Chen, Yanling, Luo, Ziyi, Liang, Li, Liu, Yunjiao, Xu, Anjie, Tong, Xiqin, Can, Can, Ding, Lu, Tu, Honglei, Tan, Yuxin, Jiang, Hongqiang, Liu, Xiaoyan, Shen, Hui, Liu, Li, Pan, Yunbao, Wei, Yongchang, Zhou, Fuling
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901913/
https://ncbi.nlm.nih.gov/pubmed/31849658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01396
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