High glucose causes apoptosis of rabbit corneal epithelial cells involving activation of PERK-eIF2α-CHOP-caspase-12 signaling pathway

AIM: To investigate the effect of high concentration of glucose (HCG) on double stranded RNA-activated protein kinase-like ER kinase (PERK)-eukaryotic initiation factor-2α (eIF2α)-transcription factor C/EBP homologous protein (CHOP)-cysteine aspartate specific proteinase (caspase-12) signaling pathw...

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Publicado en:Int J Ophthalmol
Autores principales: Yao, Pan-Pan, Sheng, Min-Jie, Weng, Wen-Hao, Long, Yin, Liu, Hao, Chen, Li, Lu, Jia-Jun, Rong, Ao, Li, Bing
Formato: Artigo
Lenguaje:Inglês
Publicado: International Journal of Ophthalmology Press 2019
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901899/
https://ncbi.nlm.nih.gov/pubmed/31850162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2019.12.01
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