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Pif1 family DNA helicases: a helpmate to RNase H?

An R-loop is a structure that forms when an RNA transcript stays bound to the DNA strand that encodes it and leaves the complementary strand exposed as a loop of single stranded DNA. R-loops accumulate when the processing of RNA transcripts is impaired. The failure to remove these RNA-DNA hybrids ca...

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Foilsithe in:DNA Repair (Amst)
Main Authors: Pohl, Thomas J., Zakian, Virginia A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901714/
https://ncbi.nlm.nih.gov/pubmed/31231063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.06.004
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