More than one antibody of individual B cells revealed by single-cell immune profiling

Antibodies have a common structure consisting of two identical heavy (H) and two identical light (L) chains. It is widely accepted that a single mature B cell produces a single antibody through restricted synthesis of only one V(H)DJ(H) (encoding the H-chain variable region) and one V(L)J(L) (encodi...

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Publicado no:Cell Discov
Main Authors: Shi, Zhan, Zhang, Qingyang, Yan, Huige, Yang, Ying, Wang, Pingzhang, Zhang, Yixiao, Deng, Zhenling, Yu, Meng, Zhou, Wenjing, Wang, Qianqian, Yang, Xi, Mo, Xiaoning, Zhang, Chi, Huang, Jing, Dai, Hui, Sun, Baofa, Zhao, Yongliang, Zhang, Liang, Yang, Yun-Gui, Qiu, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901605/
https://ncbi.nlm.nih.gov/pubmed/31839985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-019-0137-3
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