Epigenetic aging is accelerated in alcohol use disorder and regulated by genetic variation in APOL2

To investigate the potential role of alcohol use disorder (AUD) in aging processes, we employed Levine’s epigenetic clock (DNAm PhenoAge) to estimate DNA methylation age in 331 individuals with AUD and 201 healthy controls (HC). We evaluated the effects of heavy, chronic alcohol consumption on epige...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Luo, Audrey, Jung, Jeesun, Longley, Martha, Rosoff, Daniel B., Charlet, Katrin, Muench, Christine, Lee, Jisoo, Hodgkinson, Colin A., Goldman, David, Horvath, Steve, Kaminsky, Zachary A., Lohoff, Falk W.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901591/
https://ncbi.nlm.nih.gov/pubmed/31466081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0500-y
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