Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum

Human myeloid-derived growth factor (hMYDGF) is a 142-residue protein with a C-terminal endoplasmic reticulum (ER) retention sequence (ERS). Extracellular MYDGF mediates cardiac repair in mice after anoxic injury. Although homologs of hMYDGF are found in eukaryotes as distant as protozoans, its stru...

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Publicado no:Nat Commun
Main Authors: Bortnov, Valeriu, Tonelli, Marco, Lee, Woonghee, Lin, Ziqing, Annis, Douglas S., Demerdash, Omar N., Bateman, Alex, Mitchell, Julie C., Ge, Ying, Markley, John L., Mosher, Deane F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901522/
https://ncbi.nlm.nih.gov/pubmed/31819058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13577-5
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