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Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity
The human AdipoR1 and AdipoR2 proteins, as well as their C. elegans homolog PAQR-2, protect against cell membrane rigidification by exogenous saturated fatty acids by regulating phospholipid composition. Here, we show that mutations in the C. elegans gene acs-13 help to suppress the phenotypes of pa...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901333/ https://ncbi.nlm.nih.gov/pubmed/31769755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47733 |
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