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Cobalt Chloride Induced Apoptosis by Inhibiting GPC3 Expression via the HIF-1α/c-Myc Axis in HepG2 Cells
PURPOSE: To investigate the role of glypican-3 (GPC3) in cobalt chloride (CoCl(2))-induced cell apoptosis in hepatocellular carcinoma. METHODS: HepG2 cells were treated with CoCl(2) in the absence or presence of GPC3 plasmid transfection. Cell viability and apoptosis were assessed by MTT assay and f...
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| Pubblicato in: | Onco Targets Ther |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6901039/ https://ncbi.nlm.nih.gov/pubmed/31824173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S227215 |
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