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Texture Analysis of Fluorescence Lifetime Images of AT- and GC-rich Regions in Nuclei

We used intensity and fluorescence lifetime microscopy (FLIM) of 3T3 nuclei to investigate the existence of AT-rich and GC-rich regions of the nuclear DNA. Hoechst 33258 (Ho) and 7-aminoactinomycin D (7-AAD) were used as fluorescence probes specific for AT and GC base pairs, respectively. YOYO-1 (Yo...

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Detalles Bibliográficos
Publicado en:J Histochem Cytochem
Main Authors: Murata, Shin-ichi, Herman, Petr, Lakowicz, Joseph R.
Formato: Artigo
Idioma:Inglês
Publicado: 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901026/
https://ncbi.nlm.nih.gov/pubmed/11668197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/002215540104901112
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