Identification of Acer2 as a First Susceptibility Gene for Lithium-Induced Nephrogenic Diabetes Insipidus in Mice

BACKGROUND: Lithium, mainstay treatment for bipolar disorder, causes nephrogenic diabetes insipidus and hypercalcemia in about 20% and 10% of patients, respectively, and may lead to acidosis. These adverse effects develop in only a subset of patients treated with lithium, suggesting genetic factors...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: de Groot, Theun, Ebert, Lena K., Christensen, Birgitte Mønster, Andralojc, Karolina, Cheval, Lydie, Doucet, Alain, Mao, Cungui, Baumgarten, Ruben, Low, Benjamin E., Sandhoff, Roger, Wiles, Michael V., Deen, Peter M.T., Korstanje, Ron
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2019
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900794/
https://ncbi.nlm.nih.gov/pubmed/31558682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018050549
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