Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection

Mycobacterial AdnAB is a heterodimeric helicase–nuclease that initiates homologous recombination by resecting DNA double-strand breaks (DSBs). The AdnA and AdnB subunits are each composed of an N-terminal motor domain and a C-terminal nuclease domain. Here we report cryoelectron microscopy (cryo-EM)...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Jia, Ning, Unciuleac, Mihaela C., Xue, Chaoyou, Greene, Eric C., Patel, Dinshaw J., Shuman, Stewart
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900545/
https://ncbi.nlm.nih.gov/pubmed/31740608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913546116
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker