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A locomotor assay reveals deficits in heterozygous Parkinson’s disease model and proprioceptive mutants in adult Drosophila

Severe locomotor impairment is a common phenotype of neurodegenerative disorders such as Parkinson’s disease (PD). Drosophila models of PD, studied for more than a decade, have helped in understanding the interaction between various genetic factors, such as parkin and PINK1, in this disease. To char...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Aggarwal, Aman, Reichert, Heinrich, VijayRaghavan, K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900508/
https://ncbi.nlm.nih.gov/pubmed/31748267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807456116
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