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Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention

BACKGROUND: The application of MTX as a chemotherapy agent and immune system suppressant has various side effects. Crocin, a xanthine derivative plant, has many therapeutic benefits. This study was planned to assess the effect of crocin on renal toxicity of MTX in a rat model. METHODS: Forty eight r...

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Publicat a:Iran Biomed J
Autors principals: Jalili, Cyrus, Ghanbari, Ali, Roshankhah, Shiva, Salahshoor, Mohammad Reza
Format: Artigo
Idioma:Inglês
Publicat: Pasteur Institute of Iran 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900476/
https://ncbi.nlm.nih.gov/pubmed/31454862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/ibj.24.1.39
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