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Age‐ and disease‐specific changes of the kynurenine pathway in Parkinson’s and Alzheimer’s disease

The kynurenine (Kyn) pathway, which regulates neuroinflammation and N‐methyl‐d‐aspartate receptor activation, is implicated in Parkinson’s disease (PD) and Alzheimer’s disease (AD). Age‐related changes in Kyn metabolism and altered cerebral Kyn uptake along large neutral amino acid transporters, cou...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Sorgdrager, Freek J. H., Vermeiren, Yannick, Van Faassen, Martijn, van der Ley, Claude, Nollen, Ellen A. A., Kema, Ido P., De Deyn, Peter P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899862/
https://ncbi.nlm.nih.gov/pubmed/31376341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14843
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