Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF‐1

BACKGROUND AND AIMS: Bile acids are now accepted as central signalling molecules for the regulation of glucose, amino acid and lipid metabolism. Adrenal gland cortex cells express the bile acid receptors farnesoid X receptor (FXR), the G protein‐coupled bile acid receptor (TGR5) and the sphingosine‐...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Liu, Lei, Panzitt, Katrin, Racedo, Silvia, Wagner, Martin, Platzer, Wolfgang, Zaufel, Alex, Theiler‐Schwetz, Verena, Obermayer‐Pietsch, Barbara, Müller, Helmut, Höfler, Gerald, Heinemann, Akos, Zollner, Gernot, Fickert, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Autoimmune and Cholestatic Liver Diseases
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899711/
https://ncbi.nlm.nih.gov/pubmed/30664326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14052
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