Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice

Respiratory failure is a life-threatening problem for pre-term and term infants, yet many causes remain unknown. Here, we present evidence that whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (Wfdc2), a protease inhibitor previously unrecognized in respiratory disease, may...

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Vydáno v:Dis Model Mech
Hlavní autoři: Nakajima, Kuniko, Ono, Michio, Radović, Uroš, Dizdarević, Selma, Tomizawa, Shin-ichi, Kuroha, Kazushige, Nagamatsu, Go, Hoshi, Ikue, Matsunaga, Risa, Shirakawa, Takayuki, Kurosawa, Takeyuki, Miyazaki, Yasunari, Seki, Masahide, Suzuki, Yutaka, Koseki, Haruhiko, Nakamura, Masataka, Suda, Toshio, Ohbo, Kazuyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899016/
https://ncbi.nlm.nih.gov/pubmed/31562139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.040139
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