Antiviral activity of mitoxantrone dihydrochloride against human herpes simplex virus mediated by suppression of the viral immediate early genes

BACKGROUND: HSV-1 is a common pathogen that infects 50–90% of the human population worldwide. HSV-1 causes numerous infection-related diseases, some of which are severely life-threatening. There are antiviral medications with activity against HSV-1. However, with the emergence of drug-resistant muta...

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Vydáno v:BMC Microbiol
Hlavní autoři: Huang, Qiang, Hou, Jue, Yang, Peng, Yan, Jun, Yu, Xiaoliang, Zhuo, Ying, He, Sudan, Xu, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898960/
https://ncbi.nlm.nih.gov/pubmed/31812160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1639-8
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