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Sex differences in opioid reinforcement under a fentanyl vs. food choice procedure in rats

Clinical evidence suggest that men are more sensitive than women to the abuse-related effects of mu-opioid agonists. In contrast, preclinical studies suggest the opposite sex difference. The aim of the present study was to clarify this discrepancy using a fentanyl vs. diluted Ensure(®) choice proced...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Townsend, E. Andrew, Negus, S. Stevens, Caine, S. Barak, Thomsen, Morgane, Banks, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898628/
https://ncbi.nlm.nih.gov/pubmed/30818323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0356-1
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