Manipulation of a genetically and spatially defined sub-population of BDNF-expressing neurons potentiates learned fear and decreases hippocampal-prefrontal synchrony in mice

Brain-derived neurotrophic factor (BDNF) signaling regulates synaptic plasticity in the hippocampus (HC) and prefrontal cortex (PFC), and has been extensively linked with fear memory expression in rodents. Notably, disrupting BDNF production from promoter IV-derived transcripts enhances fear express...

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Bibliographic Details
Published in:Neuropsychopharmacology
Main Authors: Hallock, Henry L., Quillian, Henry M., Mai, Yishan, Maynard, Kristen R., Hill, Julia L., Martinowich, Keri
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898598/
https://ncbi.nlm.nih.gov/pubmed/31170726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0429-1
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