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Polymorphisms of MFGE8 are associated with susceptibility and clinical manifestations through gene expression modulation in Koreans with systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is characterized by impaired clearance of apoptotic cells. Milk fat globule epidermal growth factor 8 (MFGE8) is a protein that connects αvβ3 integrin on phagocytic macrophages with phosphatidylserine on apoptotic cells. We investigated whether genetic variation of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baek, Wook-Young, Woo, Ji-Min, Kim, Hyoun-Ah, Jung, Ju-Yang, Suh, Chang-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897915/
https://ncbi.nlm.nih.gov/pubmed/31811237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55061-6
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