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A homozygous mutation in GMPPB leads to centronuclear myopathy with combined pre- and postsynaptic defects of neuromuscular transmission

Mutations in GMPPB cause a wide spectrum of neuromuscular syndromes, including muscular dystrophies and congenital myasthenic syndrome. The mechanisms by which GMPPB mutations impair neuromuscular transmission however remain incompletely understood. We expand here upon a previous report of one such...

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Détails bibliographiques
Publié dans:Neuromuscul Disord
Auteurs principaux: Nicolau, Stefan, Liewluck, Teerin, Shen, Xin-Ming, Selcen, Duygu, Engel, Andrew G., Milone, Margherita
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897485/
https://ncbi.nlm.nih.gov/pubmed/31378432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2019.07.001
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