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Full-length human cytomegalovirus terminase pUL89 adopts a two-domain structure specific for DNA packaging

A key step in replication of human cytomegalovirus (HCMV) in the host cell is the generation and packaging of unit-length genomes into preformed capsids. The enzymes involved in this process are the terminases. The HCMV terminase complex consists of two terminase subunits, the ATPase pUL56 and the n...

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Pubblicato in:PLoS Pathog
Autori principali: Theiß, Janine, Sung, Min Woo, Holzenburg, Andreas, Bogner, Elke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6897398/
https://ncbi.nlm.nih.gov/pubmed/31809525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008175
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