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Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction

BACKGROUND: Beta-lapachone has been shown to exhibit potent anti-cancer effects against various cell lines. In the present study, we examined the anti-cancer effects of beta-lapachone, a quinone, against human HNE1 nasopharyngeal carcinoma cells, and also assessed its effects on cellular migration a...

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Detalhes bibliográficos
Publicado no:Med Sci Monit
Main Authors: Han, Yongqing, Shi, Dayou, Li, Jingao
Formato: Artigo
Idioma:Inglês
Publicado em: International Scientific Literature, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896749/
https://ncbi.nlm.nih.gov/pubmed/31770363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915463
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