Mononuclear but Not Polymorphonuclear Phagocyte Depletion Increases Circulation Times and Improves Mammary Tumor-Homing Efficiency of Donor Bone Marrow-Derived Monocytes

Tumor associated macrophages are an essential part of the tumor microenvironment. Consequently, bone marrow-derived monocytes (BMDMs) are continuously recruited to tumors and are therefore seen as ideal delivery vehicles with tumor-targeting properties. By using immune cell depleting agents and macr...

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Publicat a:Cancers (Basel)
Autors principals: Combes, Francis, Sofias, Alexandros Marios, Mc Cafferty, Séan, Huysmans, Hanne, De Temmerman, Joyca, Hak, Sjoerd, Meyer, Evelyne, Sanders, Niek N.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896201/
https://ncbi.nlm.nih.gov/pubmed/31717301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111752
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