The Critical Role of Hypoxic Microenvironment and Epigenetic Deregulation in Esophageal Cancer Radioresistance

Esophageal cancer (EC) is the seventh most common cancer worldwide and the sixth leading cause of death, according to Globocan 2018. Despite efforts made for therapeutic advances, EC remains highly lethal, portending a five-year overall survival of just 15–20%. Hence, the discovery of new molecular...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Macedo-Silva, Catarina, Miranda-Gonçalves, Vera, Henrique, Rui, Jerónimo, Carmen, Bravo, Isabel
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896142/
https://ncbi.nlm.nih.gov/pubmed/31739546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10110927
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