Fibroblasts in Nodular Sclerosing Classical Hodgkin Lymphoma Are Defined by a Specific Phenotype and Protect Tumor Cells from Brentuximab-Vedotin Induced Injury

Classical Hodgkin lymphoma (cHL) is one of the most common malignant lymphomas in Western Europe. The nodular sclerosing subtype of cHL (NS cHL) is characterized by a proliferation of fibroblasts in the tumor microenvironment, leading to fibrotic bands surrounding the lymphoma infiltrate. Several st...

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Udgivet i:Cancers (Basel)
Main Authors: Bankov, Katrin, Döring, Claudia, Ustaszewski, Adam, Giefing, Maciej, Herling, Marco, Cencioni, Chiara, Spallotta, Francesco, Gaetano, Carlo, Küppers, Ralf, Hansmann, Martin-Leo, Hartmann, Sylvia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896072/
https://ncbi.nlm.nih.gov/pubmed/31671543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111687
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