Targeted-Gene Sequencing to Catch Triple Negative Breast Cancer Heterogeneity before and after Neoadjuvant Chemotherapy

Triple negative breast cancer (TNBC) patients not attaining pathological Complete Response (pCR) after neo-adjuvant chemotherapy (NAC) have poor prognosis. We characterized 19 patients for somatic mutations in primary tumor biopsy and residual disease (RD) at surgery by 409 cancer-related gene seque...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Di Cosimo, Serena, Appierto, Valentina, Silvestri, Marco, Pruneri, Giancarlo, Vingiani, Andrea, Perrone, Federica, Busico, Adele, Folli, Secondo, Scaperrotta, Gianfranco, de Braud, Filippo Guglielmo, Bianchi, Giulia Valeria, Cavalieri, Stefano, Daidone, Maria Grazia, Dugo, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895966/
https://ncbi.nlm.nih.gov/pubmed/31717320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111753
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